The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism

The triosephosphate isomerase (TIM) barrel protein fold is a structurally repetitive architecture that is present in approximately 10 % of all enzymes. It is generally assumed that this ubiquity in modern proteomes reflects an essential historical role in early protein-mediated metabolism. Here, we...

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Detalles Bibliográficos
Autores principales: Goldman, Aaron David, Beatty, Joshua T., Landweber, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709378/
https://www.ncbi.nlm.nih.gov/pubmed/26733481
http://dx.doi.org/10.1007/s00239-015-9722-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709378/
https://www.ncbi.nlm.nih.gov/pubmed/26733481
http://dx.doi.org/10.1007/s00239-015-9722-8

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