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The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism
The triosephosphate isomerase (TIM) barrel protein fold is a structurally repetitive architecture that is present in approximately 10 % of all enzymes. It is generally assumed that this ubiquity in modern proteomes reflects an essential historical role in early protein-mediated metabolism. Here, we...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709378/ https://www.ncbi.nlm.nih.gov/pubmed/26733481 http://dx.doi.org/10.1007/s00239-015-9722-8 |