Cargando…

Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery

Sn2 lipase labile phospholipid prodrugs in conjunction with contact-facilitated drug delivery offer an important advancement in Nanomedicine. Many drugs incorporated into nanosystems, targeted or not, are substantially lost during circulation to the target. However, favorably altering the pharmacoki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Dipanjan, Pham, Christine TN, Weilbaecher, Katherine N, Tomasson, Michael H, Wickline, Samuel A, Lanza, Gregory M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2016
Materias:	Advanced Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709477/ https://www.ncbi.nlm.nih.gov/pubmed/26296541 http://dx.doi.org/10.1002/wnan.1355

Ejemplares similares

α(ν)β(3)-targeted Copper Nanoparticles Incorporating an Sn 2 Lipase-Labile Fumagillin Prodrug for Photoacoustic Neovascular Imaging and Treatment
por: Zhang, Ruiying, et al.
Publicado: (2015)

Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using α(v)β(3)-Targeted Theranostic Nanoparticles
por: Pan, Dipanjan, et al.
Publicado: (2014)

Therapeutic Potential of Prodrugs Towards Targeted Drug Delivery
por: Mishra, Abhinav P., et al.
Publicado: (2018)

Modern Prodrug Design for Targeted Oral Drug Delivery
por: Dahan, Arik, et al.
Publicado: (2014)

Self-Assembly of pH-Labile Polymer Nanoparticles for Paclitaxel Prodrug Delivery: Formulation, Characterization, and Evaluation
por: Levit, Shani L., et al.
Publicado: (2020)

A Co-delivery System Based on a Dimeric Prodrug and Star-Shaped Polymeric Prodrug Micelles for Drug Delivery
por: Zhou, Man, et al.
Publicado: (2021)

Engineering of small-molecule lipidic prodrugs as novel nanomedicines for enhanced drug delivery
por: Huang, Lingling, et al.
Publicado: (2022)

Drug-Initiated Synthesis of Polymer Prodrugs: Combining Simplicity and Efficacy in Drug Delivery†
por: Nicolas, Julien
Publicado: (2016)

Progress in Drug Delivery to the Central Nervous System by the Prodrug Approach
por: Pavan, Barbara, et al.
Publicado: (2008)

pH-Labile Magnetic Nanocarriers for Intracellular Drug Delivery to Tumor Cells
por: Gawali, Santosh L., et al.
Publicado: (2019)

Fumagillin Prodrug Nanotherapy Suppresses Macrophage Inflammatory Response via Endothelial Nitric Oxide
por: Zhou, Hui-fang, et al.
Publicado: (2014)

Self-assembling prodrug nanotherapeutics for synergistic tumor targeted drug delivery
por: Wang, Zhiren, et al.
Publicado: (2020)

A Comparative Evaluation of Hydroxycamptothecin Drug Nanorods With and Without Methotrexate Prodrug Functionalization for Drug Delivery
por: Guo, Fuqiang, et al.
Publicado: (2016)

Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine
por: Weiss, Jason T., et al.
Publicado: (2014)

In Vitro and In Vivo Evaluation of Microparticulate Drug Delivery Systems Composed of Macromolecular Prodrugs
por: Onishi, Hiraku, et al.
Publicado: (2008)

Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system
por: Lee, Jong Bong, et al.
Publicado: (2018)

Phospholipid prodrug conjugates of insoluble chemotherapeutic agents for ultrasound targeted drug delivery
por: Márquez, Mendi G., et al.
Publicado: (2020)

The evolution of nucleosidic analogues: self-assembly of prodrugs into nanoparticles for cancer drug delivery
por: Baroud, Milad, et al.
Publicado: (2021)

Templated Assembly of pH-Labile Covalent Organic Framework Hierarchical Particles for Intracellular Drug Delivery
por: Zhou, Fangzhou, et al.
Publicado: (2022)

Encapsulation of Pt(iv) prodrugs within a Pt(ii) cage for drug delivery
por: Zheng, Yao-Rong, et al.
Publicado: (2015)

Photoresponsive Block Copolymer Prodrug Nanoparticles as Delivery Vehicle for Single and Dual Anticancer Drugs
por: Biswas, Gargi, et al.
Publicado: (2017)

Phospholipid-Based Prodrugs for Colon-Targeted Drug Delivery: Experimental Study and In-Silico Simulations
por: Markovic, Milica, et al.
Publicado: (2019)

Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products
por: Markovic, Milica, et al.
Publicado: (2020)

Cellular Trafficking of Sn-2 Phosphatidylcholine Prodrugs Studied with Fluorescence Lifetime Imaging and Super-resolution Microscopy
por: Maji, Dolonchampa, et al.
Publicado: (2018)

Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel
por: Ding, Dawei, et al.
Publicado: (2019)

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery
por: Zheng, Yao-Rong, et al.
Publicado: (2014)

Functional cRGD-Conjugated Polymer Prodrug for Targeted Drug Delivery to Liver Cancer Cells
por: Zhou, Ru, et al.
Publicado: (2022)

Induction of WNT16 via Peptide-mRNA Nanoparticle-Based Delivery Maintains Cartilage Homeostasis
por: Yan, Huimin, et al.
Publicado: (2020)

Integrated prodrug micelles with two-photon bioimaging and pH-triggered drug delivery for cancer theranostics
por: Xu, Hong, et al.
Publicado: (2020)

A pH-Responsive Zwitterionic Polyurethane Prodrug as Drug Delivery System for Enhanced Cancer Therapy
por: He, Qian, et al.
Publicado: (2021)

Use of Self-Assembled Colloidal Prodrug Nanoparticles for Controlled Drug Delivery of Anticancer, Antifibrotic and Antibacterial Mitomycin
por: Abdelghafour, Mohamed M., et al.
Publicado: (2022)

Novel Approaches in Formulation and Drug Delivery using Contact Lenses
por: Singh, Kishan, et al.
Publicado: (2011)

Contact Lenses as Ophthalmic Drug Delivery Systems: A Review
por: Franco, Paola, et al.
Publicado: (2021)

Soft Contact Lenses as Drug Delivery Systems: A Review
por: Rykowska, Iwona, et al.
Publicado: (2021)

Preparation of biocompatible heat-labile enterotoxin subunit B-bovine serum albumin nanoparticles for improving tumor-targeted drug delivery via heat-labile enterotoxin subunit B mediation
por: Zhao, Liang, et al.
Publicado: (2014)

A Technology for Anti-Thrombogenic Drug Coating of Small-Diameter Biodegradable Vascular Prostheses
por: Antonova, L.V., et al.
Publicado: (2020)

Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs
por: Wang, Yayue, et al.
Publicado: (2020)

Bioreducible and acid-labile poly(amido amine)s for efficient gene delivery
por: Yu, Zhi-Qiang, et al.
Publicado: (2012)

Soft Alkyl Ether Prodrugs of a Model Phenolic Drug: The Effect of Incorporation of Ethyleneoxy Groups on Transdermal Delivery
por: Thomas, Joshua Denver, et al.
Publicado: (2009)

In vivo and in vitro evaluation of dihydroartemisinin prodrug nanocomplexes as a nano-drug delivery system: characterization, pharmacokinetics and pharmacodynamics
por: Ren, Guolian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vu4atmvjl6p0efl63ajf5qdq5k