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The Coadministration of N-Acetylcysteine Ameliorates the Effects of Arsenic Trioxide on the Male Mouse Genital System

Arsenic trioxide (As(2)O(3)) has shown effectiveness in treatment of leukemia but is also associated with reproductive toxicity. Since remediation with N-acetylcysteine (NAC) may mitigate the adverse effects caused by exposure, we assessed the effects of As(2)O(3) and its potential reversibility aft...

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Detalles Bibliográficos
Autores principales: da Silva, Raquel Frenedoso, Borges, Cibele dos Santos, Villela e Silva, Patrícia, Missassi, Gabriela, Kiguti, Luiz Ricardo Almeida, Pupo, André Sampaio, Barbosa Junior, Fernando, Anselmo-Franci, Janete Aparecida, Kempinas, Wilma De Grava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709715/
https://www.ncbi.nlm.nih.gov/pubmed/26839632
http://dx.doi.org/10.1155/2016/4257498