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The Coadministration of N-Acetylcysteine Ameliorates the Effects of Arsenic Trioxide on the Male Mouse Genital System
Arsenic trioxide (As(2)O(3)) has shown effectiveness in treatment of leukemia but is also associated with reproductive toxicity. Since remediation with N-acetylcysteine (NAC) may mitigate the adverse effects caused by exposure, we assessed the effects of As(2)O(3) and its potential reversibility aft...
Autores principales: | da Silva, Raquel Frenedoso, Borges, Cibele dos Santos, Villela e Silva, Patrícia, Missassi, Gabriela, Kiguti, Luiz Ricardo Almeida, Pupo, André Sampaio, Barbosa Junior, Fernando, Anselmo-Franci, Janete Aparecida, Kempinas, Wilma De Grava |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709715/ https://www.ncbi.nlm.nih.gov/pubmed/26839632 http://dx.doi.org/10.1155/2016/4257498 |
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