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TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described. In this study, both in vitro (HPCs cocultured with hepatic stellate cells (HSCs)...

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Detalles Bibliográficos
Autores principales: Yang, Ai-Ting, Hu, Dou-Dou, Wang, Ping, Cong, Min, Liu, Tian-Hui, Zhang, Dong, Sun, Ya-Meng, Zhao, Wen-Shan, Jia, Ji-Dong, You, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709730/
https://www.ncbi.nlm.nih.gov/pubmed/26839553
http://dx.doi.org/10.1155/2016/1492694