Cargando…

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis

BACKGROUND: The receptor for advanced glycation end products (RAGE) has been found to interact with amyloid β (Aβ). Although RAGE does not have any kinase motifs in its cytosolic domain, the interaction between RAGE and Aβ triggers multiple cellular signaling involved in Alzheimer’s disease (AD). Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Yoonhee, Kim, Chaeyoung, Son, Sung Min, Song, Hyundong, Hong, Hyun Seok, Han, Sun-ho, Mook-Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709948/
https://www.ncbi.nlm.nih.gov/pubmed/26758977
http://dx.doi.org/10.1186/s13024-016-0068-5