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The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis
BACKGROUND: The receptor for advanced glycation end products (RAGE) has been found to interact with amyloid β (Aβ). Although RAGE does not have any kinase motifs in its cytosolic domain, the interaction between RAGE and Aβ triggers multiple cellular signaling involved in Alzheimer’s disease (AD). Ho...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709948/ https://www.ncbi.nlm.nih.gov/pubmed/26758977 http://dx.doi.org/10.1186/s13024-016-0068-5 |