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Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells

BACKGROUND: Hypoacetylation on histone H3 of human prostate cancer cells has been described. Little is known about the modifications of other histones from prostate cancer cells. METHODS: Histones were isolated from the prostate cancer cell line DU-145 and the non-malignant prostatic cell line RC170...

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Detalles Bibliográficos
Autores principales: Cang, Shundong, Xu, Xiaobin, Ma, Yuehua, Liu, Delong, Chiao, J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709959/
https://www.ncbi.nlm.nih.gov/pubmed/26759222
http://dx.doi.org/10.1186/s13045-016-0233-x