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Sickle haemoglobin, haemoglobin C and malaria mortality feedbacks

BACKGROUND: Sickle haemoglobin (HbS) and haemoglobin C (HbC) are both caused by point mutations in the beta globin gene, and both offer substantial malaria protection. Despite the fact that the blood disorder caused by homozygosity for HbC is much less severe than that caused by homozygosity for HbS...

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Detalles Bibliográficos
Autores principales: Gonçalves, Bronner P., Gupta, Sunetra, Penman, Bridget S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709991/
https://www.ncbi.nlm.nih.gov/pubmed/26753833
http://dx.doi.org/10.1186/s12936-015-1077-5