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MicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical use

In the past two decades, microRNAs have emerged as crucial mediators of organ development and human disease. Here, we discuss their role as drivers or suppressors of the hallmarks of cancer during tumorigenesis and progression, in defining interpatient heterogeneity and the promise of therapeutic ap...

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Detalles Bibliográficos
Autores principales: Nana-Sinkam, S Patrick, Croce, Carlo M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709998/
https://www.ncbi.nlm.nih.gov/pubmed/25315999
http://dx.doi.org/10.1186/s13059-014-0445-8