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Renin gene rs1464816 polymorphism contributes to chronic kidney disease progression in ADPKD

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disorder and is a common genetic cause of chronic renal failure in children and adults. The enzyme renin plays a key role in the RAAS cascade and an important role in the development of hypertension and progression of re...

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Detalles Bibliográficos
Autores principales: Ramanathan, Gnanasambandan, Elumalai, Ramprasad, Periyasamy, Soundararajan, Lakkakula, Bhaskar V. K. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710007/
https://www.ncbi.nlm.nih.gov/pubmed/26753721
http://dx.doi.org/10.1186/s12929-015-0217-0