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Renin gene rs1464816 polymorphism contributes to chronic kidney disease progression in ADPKD
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disorder and is a common genetic cause of chronic renal failure in children and adults. The enzyme renin plays a key role in the RAAS cascade and an important role in the development of hypertension and progression of re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710007/ https://www.ncbi.nlm.nih.gov/pubmed/26753721 http://dx.doi.org/10.1186/s12929-015-0217-0 |