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CRTAM determines the CD4(+) cytotoxic T lymphocyte lineage
Naive T cells differentiate into various effector T cells, including CD4(+) helper T cell subsets and CD8(+) cytotoxic T cells (CTL). Although cytotoxic CD4(+) T cells (CD4(+)CTL) also develop from naive T cells, the mechanism of development is elusive. We found that a small fraction of CD4(+) T cel...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710199/ https://www.ncbi.nlm.nih.gov/pubmed/26694968 http://dx.doi.org/10.1084/jem.20150519 |