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E-selectin ligand complexes adopt an extended high-affinity conformation

E-selectin is a cell-adhesion molecule of the vascular endothelium that promotes essential leukocyte rolling in the early inflammatory response by binding to glycoproteins containing the tetrasaccharide sialyl Lewis(x) (sLe(x)). Efficient leukocyte recruitment under vascular flow conditions depends...

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Detalles Bibliográficos
Autores principales: Preston, Roland C., Jakob, Roman P., Binder, Florian P.C., Sager, Christoph P., Ernst, Beat, Maier, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710209/
https://www.ncbi.nlm.nih.gov/pubmed/26117840
http://dx.doi.org/10.1093/jmcb/mjv046