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E-selectin ligand complexes adopt an extended high-affinity conformation
E-selectin is a cell-adhesion molecule of the vascular endothelium that promotes essential leukocyte rolling in the early inflammatory response by binding to glycoproteins containing the tetrasaccharide sialyl Lewis(x) (sLe(x)). Efficient leukocyte recruitment under vascular flow conditions depends...
Autores principales: | Preston, Roland C., Jakob, Roman P., Binder, Florian P.C., Sager, Christoph P., Ernst, Beat, Maier, Timm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710209/ https://www.ncbi.nlm.nih.gov/pubmed/26117840 http://dx.doi.org/10.1093/jmcb/mjv046 |
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