Specific gyrA gene mutations predict poor treatment outcome in MDR-TB

OBJECTIVES: Mutations in the gyrase genes cause fluoroquinolone resistance in Mycobacterium tuberculosis. However, the predictive value of these markers for clinical outcomes in patients with MDR-TB is unknown to date. The objective of this study was to determine molecular markers and breakpoints pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Rigouts, L., Coeck, N., Gumusboga, M., de Rijk, W. B., Aung, K. J. M., Hossain, M. A., Fissette, K., Rieder, H. L., Meehan, C. J., de Jong, B. C., Van Deun, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710215/
https://www.ncbi.nlm.nih.gov/pubmed/26604243
http://dx.doi.org/10.1093/jac/dkv360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710215/
https://www.ncbi.nlm.nih.gov/pubmed/26604243
http://dx.doi.org/10.1093/jac/dkv360

Ejemplares similares