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Physical limits on kinesin-5–mediated chromosome congression in the smallest mitotic spindles

A characteristic feature of mitotic spindles is the congression of chromosomes near the spindle equator, a process mediated by dynamic kinetochore microtubules. A major challenge is to understand how precise, submicrometer-scale control of kinetochore micro­tubule dynamics is achieved in the smalles...

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Detalles Bibliográficos
Autores principales: McCoy, Kelsey M., Tubman, Emily S., Claas, Allison, Tank, Damien, Clancy, Shelly Applen, O’Toole, Eileen T., Berman, Judith, Odde, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710232/
https://www.ncbi.nlm.nih.gov/pubmed/26354423
http://dx.doi.org/10.1091/mbc.E14-10-1454