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Probability-based particle detection that enables threshold-free and robust in vivo single-molecule tracking

Single-molecule detection in fluorescence nanoscopy has become a powerful tool in cell biology but can present vexing issues in image analysis, such as limited signal, unspecific background, empirically set thresholds, image filtering, and false-positive detection limiting overall detection efficien...

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Detalles Bibliográficos
Autores principales: Smith, Carlas S., Stallinga, Sjoerd, Lidke, Keith A., Rieger, Bernd, Grunwald, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710236/
https://www.ncbi.nlm.nih.gov/pubmed/26424801
http://dx.doi.org/10.1091/mbc.E15-06-0448