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Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine

PURPOSE: To formulate hydroxypropyl methylcellulose-stabilized self-emulsifying solid dispersible carriers of noscapine to enhance oral bioavailability. METHODS: Formulation of noscapine (Nos) self-emulsifying solid dispersible microparticles (SESDs) was afforded by emulsification using an optimized...

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Detalles Bibliográficos
Autores principales: Andey, Terrick, Patel, Apurva, Marepally, Srujan, Chougule, Mahavir, Spencer, Shawn D., Rishi, Arun K., Singh, Mandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710382/
https://www.ncbi.nlm.nih.gov/pubmed/26757437
http://dx.doi.org/10.1371/journal.pone.0146804