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Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality

BACKGROUND: With epigenome-wide mapping of DNA methylation, a number of novel smoking-associated loci have been identified. OBJECTIVES: We aimed to assess dose–response relationships of methylation at the top hits from the epigenome-wide methylation studies with smoking exposure as well as with tota...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Schöttker, Ben, Florath, Ines, Stock, Christian, Butterbach, Katja, Holleczek, Bernd, Mons, Ute, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710597/
https://www.ncbi.nlm.nih.gov/pubmed/26017925
http://dx.doi.org/10.1289/ehp.1409020