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Optimization of an in vitro human blood–brain barrier model: Application to blood monocyte transmigration assays

The blood–brain barrier (BBB) is a selectively permeable barrier that separates the circulating blood from the extracellular fluid of the brain and is an essential component in brain homeostasis. In vitro BBB models are valuable supporting tools that can precede and complement animal and human studi...

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Detalles Bibliográficos
Autores principales: Paradis, Alexandre, Leblanc, David, Dumais, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710797/
https://www.ncbi.nlm.nih.gov/pubmed/26865992
http://dx.doi.org/10.1016/j.mex.2015.11.009