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Optimization of an in vitro human blood–brain barrier model: Application to blood monocyte transmigration assays
The blood–brain barrier (BBB) is a selectively permeable barrier that separates the circulating blood from the extracellular fluid of the brain and is an essential component in brain homeostasis. In vitro BBB models are valuable supporting tools that can precede and complement animal and human studi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710797/ https://www.ncbi.nlm.nih.gov/pubmed/26865992 http://dx.doi.org/10.1016/j.mex.2015.11.009 |