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The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR2
IgLON proteins are GPI anchored adhesion molecules that control neurite outgrowth. In particular, Negr1 down-regulation negatively influences neuronal arborization in vitro and in vivo. In the present study, we found that the metalloprotease ADAM10 releases Negr1 from neuronal membrane. Ectodomain s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710852/ https://www.ncbi.nlm.nih.gov/pubmed/26793057 http://dx.doi.org/10.3389/fnmol.2015.00089 |