The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertension

Human genetic discoveries offer a powerful method to implicate pathways of major importance to disease pathobiology and hence provide targets for pharmacological intervention. The genetics of pulmonary arterial hypertension (PAH) strongly implicates loss-of-function of the bone morphogenetic protein...

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Detalles Bibliográficos
Autores principales: Ormiston, Mark L., Upton, Paul D., Li, Wei, Morrell, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bloomsbury Qatar Foundation Journals 2015
Materias:
Mechanisms of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710869/
https://www.ncbi.nlm.nih.gov/pubmed/26779522
http://dx.doi.org/10.5339/gcsp.2015.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710869/
https://www.ncbi.nlm.nih.gov/pubmed/26779522
http://dx.doi.org/10.5339/gcsp.2015.47

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