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The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertension

Human genetic discoveries offer a powerful method to implicate pathways of major importance to disease pathobiology and hence provide targets for pharmacological intervention. The genetics of pulmonary arterial hypertension (PAH) strongly implicates loss-of-function of the bone morphogenetic protein...

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Detalles Bibliográficos
Autores principales:	Ormiston, Mark L., Upton, Paul D., Li, Wei, Morrell, Nicholas W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bloomsbury Qatar Foundation Journals 2015
Materias:	Mechanisms of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710869/ https://www.ncbi.nlm.nih.gov/pubmed/26779522 http://dx.doi.org/10.5339/gcsp.2015.47

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