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Transcriptional Activation of p53 during Cold Induced Torpor in the 13-Lined Ground Squirrel Ictidomys tridecemlineatus

The transcription factor p53 is located at the centre of multiple pathways relating the cellular response to stress. Commonly known as a tumor suppressor, it is responsible for initiating diverse actions to protect the integrity of the genome, ranging from cell cycle arrest to apoptosis. This study...

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Detalles Bibliográficos
Autores principales: Hefler, Joshua, Wu, Cheng-Wei, Storey, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710910/
https://www.ncbi.nlm.nih.gov/pubmed/26843984
http://dx.doi.org/10.1155/2015/731595