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Effect of prior exposure to dopamine agonists on treatment with gabapentin enacarbil in adults with moderate-to-severe primary restless legs syndrome: pooled analyses from 3 randomized trials

BACKGROUND: Dopamine agonists (DAs) are a first-line therapy for moderate-to-severe restless legs syndrome (RLS), but these treatments may lead to complications, such as augmentation and impulse control disorders, requiring switching to another therapeutic class. Here we assess efficacy and tolerabi...

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Detalles Bibliográficos
Autores principales: Ondo, William G, Hermanowicz, Neal, Borreguero, Diego García, Jaros, Mark J, Kim, Richard, Shang, Gwendoline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711039/
https://www.ncbi.nlm.nih.gov/pubmed/26788345
http://dx.doi.org/10.1186/s40734-015-0018-3