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Antitumor activity of Cetuximab in combination with Ixabepilone on triple negative breast cancer stem cells

BACKGROUND: Developing novel strategies against treatment-resistant triple negative breast cancer (TNBC) cells remains a significant challenge. The ErbB family, including epidermal growth factor receptor (EGFR), plays key roles in metastasis, tumorigenesis, cell proliferation, and drug resistance. R...

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Detalles Bibliográficos
Autores principales: Tanei, Tomonori, Choi, Dong Soon, Rodriguez, Angel A., Liang, Diana Hwang, Dobrolecki, Lacey, Ghosh, Madhumita, Landis, Melissa D., Chang, Jenny C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711100/
https://www.ncbi.nlm.nih.gov/pubmed/26757880
http://dx.doi.org/10.1186/s13058-015-0662-4