Clinical implication of thiopurine methyltransferase polymorphism in children with acute lymphoblastic leukemia: A preliminary Egyptian study

BACKGROUND: 6-mercaptopurine (6-MP) is an essential component of pediatric acute lymphoblastic leukemia (ALL) maintenance therapy. Individual variability in this drug-related toxicity could be attributed in part to genetic polymorphism thiopurine methyltransferase (TPMT). AIM: To investigate the fre...

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Detalles Bibliográficos
Autores principales: El-Rashedy, Farida H., Ragab, Seham Mohammed, Dawood, Ashraf A., Temraz, Shaymaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711227/
https://www.ncbi.nlm.nih.gov/pubmed/26811598
http://dx.doi.org/10.4103/0971-5851.171553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711227/
https://www.ncbi.nlm.nih.gov/pubmed/26811598
http://dx.doi.org/10.4103/0971-5851.171553

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