Phenylephrine preconditioning in embryonic heart H9c2 cells is mediated by up-regulation of SUR2B/Kir6.2: A first evidence for functional role of SUR2B in sarcolemmal K(ATP) channels and cardioprotection

ATP-sensitive K(+) (K(ATP)) channels were originally described in cardiomyocytes, where physiological levels of intracellular ATP keep them in a closed state. Structurally, these channels are composed of pore-forming inward rectifier, Kir6.1 or Kir6.2, and a regulatory, ATP-binding subunit, SUR1, SU...

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Detalles Bibliográficos
Autores principales: Jovanović, Sofija, Ballantyne, Thomas, Du, Qingyou, Blagojević, Miloš, Jovanović, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711337/
https://www.ncbi.nlm.nih.gov/pubmed/26556311
http://dx.doi.org/10.1016/j.biocel.2015.10.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711337/
https://www.ncbi.nlm.nih.gov/pubmed/26556311
http://dx.doi.org/10.1016/j.biocel.2015.10.029

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