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Intraluminal Release of an Antifungal β-Peptide Enhances the Antifungal and Anti-Biofilm Activities of Multilayer-Coated Catheters in a Rat Model of Venous Catheter Infection

[Image: see text] Candida albicans is the most prevalent cause of hospital-acquired fungal infections and forms biofilms on indwelling medical devices that are notoriously difficult to treat or remove. We recently demonstrated that the colonization of C. albicans on the surfaces of catheter tube seg...

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Detalles Bibliográficos
Autores principales: Raman, Namrata, Marchillo, Karen, Lee, Myung-Ryul, Rodríguez López, Angélica de L., Andes, David R., Palecek, Sean P., Lynn, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711346/
https://www.ncbi.nlm.nih.gov/pubmed/26807439
http://dx.doi.org/10.1021/acsbiomaterials.5b00427