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Different phosphoinositide 3-kinase isoforms mediate carrageenan nociception and inflammation
Phosphoinositide 3-kinases (PI3Ks) participate in signal transduction cascades that can directly activate and sensitize nociceptors and enhance pain transmission. They also play essential roles in chemotaxis and immune cell infiltration leading to inflammation. We wished to determine which PI3K isof...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711388/ https://www.ncbi.nlm.nih.gov/pubmed/26313408 http://dx.doi.org/10.1097/j.pain.0000000000000341 |