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Different phosphoinositide 3-kinase isoforms mediate carrageenan nociception and inflammation

Phosphoinositide 3-kinases (PI3Ks) participate in signal transduction cascades that can directly activate and sensitize nociceptors and enhance pain transmission. They also play essential roles in chemotaxis and immune cell infiltration leading to inflammation. We wished to determine which PI3K isof...

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Detalles Bibliográficos
Autores principales: Pritchard, Rory A., Falk, Lovissa, Larsson, Mathilda, Leinders, Mathias, Sorkin, Linda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711388/
https://www.ncbi.nlm.nih.gov/pubmed/26313408
http://dx.doi.org/10.1097/j.pain.0000000000000341