Cargando…

Different phosphoinositide 3-kinase isoforms mediate carrageenan nociception and inflammation

Phosphoinositide 3-kinases (PI3Ks) participate in signal transduction cascades that can directly activate and sensitize nociceptors and enhance pain transmission. They also play essential roles in chemotaxis and immune cell infiltration leading to inflammation. We wished to determine which PI3K isof...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pritchard, Rory A., Falk, Lovissa, Larsson, Mathilda, Leinders, Mathias, Sorkin, Linda S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711388/ https://www.ncbi.nlm.nih.gov/pubmed/26313408 http://dx.doi.org/10.1097/j.pain.0000000000000341

Ejemplares similares

The Role of Phosphoinositide 3-Kinase Signaling in Intestinal Inflammation
por: Cahill, Catherine M., et al.
Publicado: (2012)

RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms
por: Fritsch, Ralph, et al.
Publicado: (2013)

The Phosphoinositide 3-Kinase Isoform PI3Kβ Regulates Osteoclast-Mediated Bone Resorption in Humans and Mice
por: Győri, Dávid, et al.
Publicado: (2014)

Phosphoinositide 3-Kinases as Potential Targets for Thrombosis Prevention
por: Setiabakti, Natasha M., et al.
Publicado: (2022)

Effects of Novel Isoform-Selective Phosphoinositide 3-Kinase Inhibitors on Natural Killer Cell Function
por: Yea, Sung Su, et al.
Publicado: (2014)

Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn
por: Choi, Jeong IL, et al.
Publicado: (2012)

Phosphoinositide-3-Kinase Is the Primary Mediator of Phosphoinositide-Dependent Inhibition in Mammalian Olfactory Receptor Neurons
por: Ukhanov, Kirill, et al.
Publicado: (2016)

Deficiency of p110δ Isoform of the Phosphoinositide 3 Kinase Leads to Enhanced Resistance to Leishmania donovani
por: Khadem, Forough, et al.
Publicado: (2014)

Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival
por: Juss, Jatinder K., et al.
Publicado: (2012)

The Inhibition of Phosphoinositide-3 Kinases Induce Resolution of Inflammation in a Gout Model
por: Galvão, Izabela, et al.
Publicado: (2019)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
por: Huang, Xueqin, et al.
Publicado: (2023)

Growth and Viability of Cutaneous Squamous Cell Carcinoma Cell Lines Display Different Sensitivities to Isoform-Specific Phosphoinositide 3-Kinase Inhibitors
por: Mannella, Viviana, et al.
Publicado: (2021)

Expression of Phosphoinositide-Specific Phospholipase C Isoforms in Native Endothelial Cells
por: Béziau, Delphine M., et al.
Publicado: (2015)

The Role of Carrageenan and Carboxymethylcellulose in the Development of Intestinal Inflammation
por: Martino, John Vincent, et al.
Publicado: (2017)

Inhibitory Effects of Carrageenans on Endotoxin-Induced Inflammation
por: Yermak, Irina M., et al.
Publicado: (2020)

Tyrosol Suppresses Allergic Inflammation by Inhibiting the Activation of Phosphoinositide 3-Kinase in Mast Cells
por: Je, In-Gyu, et al.
Publicado: (2015)

Involvement of Class II Phosphoinositide 3-Kinase α-Isoform in Antigen-Induced Degranulation in RBL-2H3 Cells
por: Nigorikawa, Kiyomi, et al.
Publicado: (2014)

Sinularin from Indigenous Soft Coral Attenuates Nociceptive Responses and Spinal Neuroinflammation in Carrageenan-Induced Inflammatory Rat Model
por: Huang, Shi-Ying, et al.
Publicado: (2012)

Noncanonical regulation of insulin-mediated ERK activation by phosphoinositide 3-kinase γ
por: Mohan, Maradumane L., et al.
Publicado: (2017)

Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
por: Chen, Chun-Liang, et al.
Publicado: (2023)

Phosphoinositide 3-Kinase Inhibitor-Induced Hyperglycemia
por: Shey, Susan, et al.
Publicado: (2021)

Human V-ATPase a-subunit isoforms bind specifically to distinct phosphoinositide phospholipids
por: Mitra, Connie, et al.
Publicado: (2023)

Blockade of Inflammation and Airway Hyperresponsiveness in Immune-sensitized Mice by Dominant-Negative Phosphoinositide 3-Kinase–TAT
por: Myou, Shigeharu, et al.
Publicado: (2003)

Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice—role of phosphoinositide 3-kinase gamma
por: Lang, Guang-Ping, et al.
Publicado: (2020)

The role of phosphoinositide 3-kinase subunits in chronic thyroiditis
por: Wojciechowska-Durczynska, Katarzyna, et al.
Publicado: (2012)

Phosphoinositide 3-kinase: friend and foe in cardiovascular disease
por: Ghigo, Alessandra, et al.
Publicado: (2015)

The phosphoinositide 3-kinase pathway and therapy resistance in cancer
por: Brown, Kristin K., et al.
Publicado: (2015)

Phosphoinositides, kinases and adaptors coordinating endocytosis in Trypanosoma brucei
por: Manna, Paul T, et al.
Publicado: (2016)

Multiple Functions of Phosphoinositide-3 Kinase Enhancer (PIKE)
por: Chan, Chi Bun, et al.
Publicado: (2010)

Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment
por: Gyori, David, et al.
Publicado: (2017)

Psoriasiform eruptions secondary to phosphoinositide 3-kinase inhibition
por: Dewan, Anna K., et al.
Publicado: (2019)

Phosphoinositide 3′-Kinase γ Facilitates Polyomavirus Infection
por: Clark, Paul, et al.
Publicado: (2020)

Carrageenan: Response
por: Tobacman, J
Publicado: (2002)

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation
por: Yamaguchi, Hideki, et al.
Publicado: (2011)

Nociceptive Sensory Neurons Drive Interleukin-23 Mediated Psoriasiform Skin Inflammation
por: Riol-Blanco, Lorena, et al.
Publicado: (2014)

Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin
por: Yang, Nicole J., et al.
Publicado: (2021)

Phosphoinositide 3-kinase-δ regulates fungus-induced allergic lung inflammation through endoplasmic reticulum stress
por: Lee, Kyung Sun, et al.
Publicado: (2016)

Targeted polypharmacology: Discovery of dual inhibitors of tyrosine and phosphoinositide kinases
por: Apsel, Beth, et al.
Publicado: (2008)

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?
por: McGonnell, Imelda M., et al.
Publicado: (2012)

Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis
por: Silió, Virginia, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_21tdai8lgkd3r2cv5o80eobmst