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Ly6G-mediated depletion of neutrophils is dependent on macrophages

Antibody-mediated depletion of neutrophils is commonly used to study neutropenia. However, the mechanisms by which antibodies deplete neutrophils have not been well defined. We noticed that mice deficient in complement and macrophages had blunted neutrophil depletion in response to anti-Ly6G monoclo...

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Detalles Bibliográficos
Autores principales: Bruhn, Kevin W., Dekitani, Ken, Nielsen, Travis B., Pantapalangkoor, Paul, Spellberg, Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711394/
https://www.ncbi.nlm.nih.gov/pubmed/26870635
http://dx.doi.org/10.1016/j.rinim.2015.12.001