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Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger

Ebola virus (EBOV) is a highly pathogenic filovirus that causes hemorrhagic fever in humans and animals. Currently, how EBOV fuses its envelope membrane within an endosomal membrane to cause infection is poorly understood. We successfully measure cell-cell fusion mediated by the EBOV fusion protein,...

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Detalles Bibliográficos
Autores principales: Markosyan, Ruben M., Miao, Chunhui, Zheng, Yi-Min, Melikyan, Gregory B., Liu, Shan-Lu, Cohen, Fredric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711667/
https://www.ncbi.nlm.nih.gov/pubmed/26730950
http://dx.doi.org/10.1371/journal.ppat.1005373