Cargando…

Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger

Ebola virus (EBOV) is a highly pathogenic filovirus that causes hemorrhagic fever in humans and animals. Currently, how EBOV fuses its envelope membrane within an endosomal membrane to cause infection is poorly understood. We successfully measure cell-cell fusion mediated by the EBOV fusion protein,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Markosyan, Ruben M., Miao, Chunhui, Zheng, Yi-Min, Melikyan, Gregory B., Liu, Shan-Lu, Cohen, Fredric S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711667/ https://www.ncbi.nlm.nih.gov/pubmed/26730950 http://dx.doi.org/10.1371/journal.ppat.1005373

Ejemplares similares

The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion
por: Markosyan, Ruben M., et al.
Publicado: (2021)

Negative Potentials Across Biological Membranes Promote Fusion by Class II and Class III Viral Proteins
por: Markosyan, Ruben M., et al.
Publicado: (2010)

An exploration of conditions proposed to trigger the Ebola virus glycoprotein for fusion
por: Fénéant, Lucie, et al.
Publicado: (2019)

The Transmembrane Domain and Acidic Lipid Flip-Flop Regulates Voltage-Dependent Fusion Mediated by Class II and III Viral Proteins
por: Markosyan, Ruben M., et al.
Publicado: (2013)

Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion
por: Melikyan, Grigory B., et al.
Publicado: (2000)

Ebola Virus Glycoprotein Needs an Additional Trigger, beyond Proteolytic Priming for Membrane Fusion
por: Bale, Shridhar, et al.
Publicado: (2011)

Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes
por: Suddala, Krishna C., et al.
Publicado: (2019)

The Roles of Histidines and Charged Residues as Potential Triggers of a Conformational Change in the Fusion Loop of Ebola Virus Glycoprotein
por: Lee, Jinwoo, et al.
Publicado: (2016)

Membrane Fusion and Cell Entry of XMRV Are pH-Independent and Modulated by the Envelope Glycoprotein's Cytoplasmic Tail
por: Côté, Marceline, et al.
Publicado: (2012)

Reversible conformational change in herpes simplex virus glycoprotein B with fusion-from-without activity is triggered by mildly acidic pH
por: Siekavizza-Robles, Carlos R, et al.
Publicado: (2010)

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: Stability and pH effects
por: Harrison, Joseph S, et al.
Publicado: (2011)

Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection
por: Iampietro, Mathieu, et al.
Publicado: (2017)

The Ebola-Glycoprotein Modulates the Function of Natural Killer Cells
por: Edri, Avishay, et al.
Publicado: (2018)

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway
por: Spence, Jennifer S., et al.
Publicado: (2016)

Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca(2+), and receptor binding
por: Das, Dibyendu Kumar, et al.
Publicado: (2020)

An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells
por: Cai, Yingyun, et al.
Publicado: (2021)

Ginkgolic acid inhibits fusion of enveloped viruses
por: Borenstein, Ronen, et al.
Publicado: (2020)

Author Correction: Ginkgolic acid inhibits fusion of enveloped viruses
por: Borenstein, Ronen, et al.
Publicado: (2020)

Recombinant Antibodies to the Ebola Virus Glycoprotein
por: Panina, A. A., et al.
Publicado: (2017)

Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells
por: Kühl, Annika, et al.
Publicado: (2011)

pH-Triggered Assembly of Endomembrane Multicompartments in Synthetic Cells
por: Lussier, Félix, et al.
Publicado: (2021)

Inner but Not Outer Membrane Leaflets Control the Transition from Glycosylphosphatidylinositol-anchored Influenza Hemagglutinin-induced Hemifusion to Full Fusion
por: Melikyan, Grigory B., et al.
Publicado: (1997)

Effects of Spontaneous Bilayer Curvature on Influenza Virus–mediated Fusion Pores
por: Razinkov, Vladimir I., et al.
Publicado: (1998)

Fusion of Mature HIV-1 Particles Leads to Complete Release of a Gag-GFP-Based Content Marker and Raises the Intraviral pH
por: Padilla-Parra, Sergi, et al.
Publicado: (2013)

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
por: Zhao, Yuguang, et al.
Publicado: (2016)

Human Immunodeficiency Virus 1 Preferentially Fuses with pH-Neutral Endocytic Vesicles in Cell Lines and Human Primary CD4+ T-Cells
por: Sharma, Manish, et al.
Publicado: (2023)

Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics
por: Durham, Natasha D., et al.
Publicado: (2020)

pH-Dependent entry of chikungunya virus fusion into mosquito cells
por: Nuckols, John T, et al.
Publicado: (2014)

Acid Trip: Zika Virus Goes Off-Pathway during pH-Triggered Membrane Fusion
por: Van Vlack, Erik R., et al.
Publicado: (2018)

Full-length Ebola glycoprotein accumulates in the endoplasmic reticulum
por: Bhattacharyya, Suchita, et al.
Publicado: (2011)

The Ebola Virus Glycoprotein Contributes to but Is Not Sufficient for Virulence In Vivo
por: Groseth, Allison, et al.
Publicado: (2012)

Requirements within the Ebola Viral Glycoprotein for Tetherin Antagonism
por: Vande Burgt, Nathan H., et al.
Publicado: (2015)

Antibody Derived Peptides for Detection of Ebola Virus Glycoprotein
por: Rodríguez-Martínez, Luis Mario, et al.
Publicado: (2015)

Ebola Virus Glycoprotein Domains Associated with Protective Efficacy
por: Bhatia, Bharti, et al.
Publicado: (2021)

The hr1 and Fusion Peptide Regions of the Subgroup B Avian Sarcoma and Leukosis Virus Envelope Glycoprotein Influence Low pH-Dependent Membrane Fusion
por: Babel, Angeline Rose, et al.
Publicado: (2007)

Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor
por: Sood, Chetan, et al.
Publicado: (2016)

Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein
por: Yi, Dongrong, et al.
Publicado: (2022)

Interferon-Induced HERC5 Inhibits Ebola Virus Particle Production and Is Antagonized by Ebola Glycoprotein
por: Paparisto, Ermela, et al.
Publicado: (2021)

Ebola Virus Glycoprotein IgG Seroprevalence in Community Previously Affected by Ebola, Sierra Leone
por: Manno, Daniela, et al.
Publicado: (2022)

Ebola virus glycoprotein stimulates IL-18–dependent natural killer cell responses
por: Wagstaffe, Helen R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bem2512muo87m1ocsr7cfo22bq