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A Cell Internalizing Antibody Targeting Capsid Protein (p24) Inhibits the Replication of HIV-1 in T Cells Lines and PBMCs: A Proof of Concept Study

There remains a need for newer therapeutic approaches to combat HIV/AIDS. Viral capsid protein p24 plays important roles in HIV pathogenesis. Peptides and small molecule inhibitors targeting p24 have shown to inhibit virus replication in treated cell. High specificity and biological stability of mon...

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Detalles Bibliográficos
Autores principales: Ali, Syed A., Teow, Sin-Yeang, Omar, Tasyriq Che, Khoo, Alan Soo-Beng, Choon, Tan Soo, Yusoff, Narazah Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711802/
https://www.ncbi.nlm.nih.gov/pubmed/26741963
http://dx.doi.org/10.1371/journal.pone.0145986