Sodium-Glucose Linked Cotransporter-2 Inhibition Does Not Attenuate Disease Progression in the Rat Remnant Kidney Model of Chronic Kidney Disease

Pharmacological inhibition of the proximal tubular sodium-glucose linked cotransporter-2 (SGLT2) leads to glycosuria in both diabetic and non-diabetic settings. As a consequence of their ability to modulate tubuloglomerular feedback, SGLT2 inhibitors, like agents that block the renin-angiotensin sys...

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Detalles Bibliográficos
Autores principales: Zhang, Yanling, Thai, Kerri, Kepecs, David M., Gilbert, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711803/
https://www.ncbi.nlm.nih.gov/pubmed/26741142
http://dx.doi.org/10.1371/journal.pone.0144640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711803/
https://www.ncbi.nlm.nih.gov/pubmed/26741142
http://dx.doi.org/10.1371/journal.pone.0144640

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