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Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts

There is currently tremendous interest in developing anti-cancer therapeutics targeting cell signaling pathways important for both cancer cell metabolism and growth. Several epidemiological studies have shown that diabetic patients taking metformin have a decreased incidence of pancreatic cancer. Th...

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Detalles Bibliográficos
Autores principales: Lipner, Matthew B., Marayati, Raoud, Deng, Yangmei, Wang, Xianxi, Raftery, Laura, O’Neil, Bert H., Yeh, Jen Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711922/
https://www.ncbi.nlm.nih.gov/pubmed/26760500
http://dx.doi.org/10.1371/journal.pone.0147113