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Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγ(null) Mice by Lentiviral Expression of NUP98-HOXA10HD

Techniques to expand human hematopoietic stem cells ex-vivo could be beneficial to the fields of clinical hematopoietic stem cell transplantation and gene therapy targeted at hematopoietic stem cells. NUP98-HOXA10HD is a relatively newly discovered fusion gene that in mouse transplant experiments ha...

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Detalles Bibliográficos
Autores principales: Abraham, Allistair, Kim, Yoon-Sang, Zhao, Huifen, Humphries, Keith, Persons, Derek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711970/
https://www.ncbi.nlm.nih.gov/pubmed/26761813
http://dx.doi.org/10.1371/journal.pone.0147059