L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice

New therapeutic modalities are needed for ovarian cancer, the most lethal gynecologic malignancy. Recent clinical trials have demonstrated the impressive therapeutic potential of adoptive therapy using chimeric antigen receptor (CAR)-redirected T cells to target hematological cancers, and emerging s...

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Detalles Bibliográficos
Autores principales: Hong, Hao, Brown, Christine E., Ostberg, Julie R., Priceman, Saul J., Chang, Wen-Chung, Weng, Lihong, Lin, Paul, Wakabayashi, Mark T., Jensen, Michael C., Forman, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711972/
https://www.ncbi.nlm.nih.gov/pubmed/26761817
http://dx.doi.org/10.1371/journal.pone.0146885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711972/
https://www.ncbi.nlm.nih.gov/pubmed/26761817
http://dx.doi.org/10.1371/journal.pone.0146885

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