Novel Endothelial Cell-Specific AQP1 Knockout Mice Confirm the Crucial Role of Endothelial AQP1 in Ultrafiltration during Peritoneal Dialysis

The water channel aquaporin-1 (AQP1) mediates about 50% ultrafiltration during a 2-hour hypertonic dwell in global AQP1 knockout (AQP1(-/-)) mice. Although AQP1 is widely expressed in various cell types including mesothelial cells, the ultrafiltration has been assumed to be mediated via endothelial...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Freichel, Marc, van der Hoeven, Frank, Nawroth, Peter Paul, Katus, Hugo, Kälble, Florian, Zitron, Edgar, Schwenger, Vedat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711985/
https://www.ncbi.nlm.nih.gov/pubmed/26760974
http://dx.doi.org/10.1371/journal.pone.0145513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711985/
https://www.ncbi.nlm.nih.gov/pubmed/26760974
http://dx.doi.org/10.1371/journal.pone.0145513

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