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Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased β1,6-N-Glycosylation and Increased Susceptibility to Galectin-3 Binding

Epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells is a crucial event in the onset of proliferative vitreoretinopathy (PVR), the most common reason for treatment failure in retinal detachment surgery. We studied alterations in the cell surface glycan expression profile up...

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Detalles Bibliográficos
Autores principales: Priglinger, Claudia S., Obermann, Jara, Szober, Christoph M., Merl-Pham, Juliane, Ohmayer, Uli, Behler, Jennifer, Gruhn, Fabian, Kreutzer, Thomas C., Wertheimer, Christian, Geerlof, Arie, Priglinger, Siegfried G., Hauck, Stefanie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712018/
https://www.ncbi.nlm.nih.gov/pubmed/26760037
http://dx.doi.org/10.1371/journal.pone.0146887