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Reversible Optogenetic Control of Subcellular Protein Localization in a Live Vertebrate Embryo

We demonstrate the utility of the phytochrome system to rapidly and reversibly recruit proteins to specific subcellular regions within specific cells in a living vertebrate embryo. Light-induced heterodimerization using the phytochrome system has previously been used as a powerful tool to dissect si...

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Detalles Bibliográficos
Autores principales: Buckley, Clare E., Moore, Rachel E., Reade, Anna, Goldberg, Anna R., Weiner, Orion D., Clarke, Jonathan D.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712025/
https://www.ncbi.nlm.nih.gov/pubmed/26766447
http://dx.doi.org/10.1016/j.devcel.2015.12.011