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Human-Mouse Chimerism Validates Human Stem Cell Pluripotency

Pluripotent stem cells are defined by their capacity to differentiate into all three tissue layers that comprise the body. Chimera formation, generated by stem cell transplantation to the embryo, is a stringent assessment of stem cell pluripotency. However, the ability of human pluripotent stem cell...

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Detalles Bibliográficos
Autores principales: Mascetti, Victoria L., Pedersen, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712187/
https://www.ncbi.nlm.nih.gov/pubmed/26712580
http://dx.doi.org/10.1016/j.stem.2015.11.017