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SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition
Sepsis-induced cardiac apoptosis is one of the major pathogenic factors in myocardial dysfunction. As it enhances numerous proinflammatory factors, lipopolysaccharide (LPS) is considered the principal mediator in this pathological process. However, the detailed mechanisms involved are unclear. In th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712245/ https://www.ncbi.nlm.nih.gov/pubmed/26659076 http://dx.doi.org/10.1007/s10495-015-1201-6 |