SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition

Sepsis-induced cardiac apoptosis is one of the major pathogenic factors in myocardial dysfunction. As it enhances numerous proinflammatory factors, lipopolysaccharide (LPS) is considered the principal mediator in this pathological process. However, the detailed mechanisms involved are unclear. In th...

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Detalles Bibliográficos
Autores principales: Jia, Zhuqing, Wang, Jiaji, Shi, Qiong, Liu, Siyu, Wang, Weiping, Tian, Yuyao, Lu, Qin, Chen, Ping, Ma, Kangtao, Zhou, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712245/
https://www.ncbi.nlm.nih.gov/pubmed/26659076
http://dx.doi.org/10.1007/s10495-015-1201-6

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