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The PTEN tumor suppressor gene and its role in lymphoma pathogenesis

The phosphatase and tensin homolog gene PTEN is one of the most frequently mutated tumor suppressor genes in human cancer. Loss of PTEN function occurs in a variety of human cancers via its mutation, deletion, transcriptional silencing, or protein instability. PTEN deficiency in cancer has been asso...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxiao, Huang, Huiqiang, Young, Ken H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712330/
https://www.ncbi.nlm.nih.gov/pubmed/26655726