Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial

AIMS: The currently available data indicate a drug–drug interaction between morphine and oral P2Y12 receptor inhibitors, when administered together. The aim of this trial was to assess the influence of infused morphine on pharmacokinetics and pharmacodynamics of ticagrelor and its active metabolite...

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Detalles Bibliográficos
Autores principales: Kubica, Jacek, Adamski, Piotr, Ostrowska, Małgorzata, Sikora, Joanna, Kubica, Julia Maria, Sroka, Wiktor Dariusz, Stankowska, Katarzyna, Buszko, Katarzyna, Navarese, Eliano Pio, Jilma, Bernd, Siller-Matula, Jolanta Maria, Marszałł, Michał Piotr, Rość, Danuta, Koziński, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Fasttrack Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712351/
https://www.ncbi.nlm.nih.gov/pubmed/26491112
http://dx.doi.org/10.1093/eurheartj/ehv547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712351/
https://www.ncbi.nlm.nih.gov/pubmed/26491112
http://dx.doi.org/10.1093/eurheartj/ehv547

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